{"id":22,"date":"2022-07-17T03:58:04","date_gmt":"2022-07-17T03:58:04","guid":{"rendered":"https:\/\/labs.bio.cmu.edu\/test\/?page_id=22"},"modified":"2026-09-09T13:45:53","modified_gmt":"2026-09-09T13:45:53","slug":"research","status":"publish","type":"page","link":"https:\/\/labs.bio.cmu.edu\/bridges\/research\/","title":{"rendered":"Research &amp; Publications"},"content":{"rendered":"<div class=\"et_pb_section_0 et_pb_section et_section_regular et_block_section\"><span class=\"et_pb_background_pattern\"><\/span>\n<div class=\"et_pb_row_0 et_pb_row et_block_row\">\n<div class=\"et_pb_column_0 et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_heading_0 et_pb_heading et_pb_module et_block_module\"><div class=\"et_pb_heading_container\"><h1 class=\"et_pb_module_header\">Research and Publications<\/h1><\/div><\/div>\n<\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_section_1 et_pb_section et_section_regular et_block_section\">\n<div class=\"et_pb_row_1 et_pb_row et_block_row\">\n<div class=\"et_pb_column_1 et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_text_0 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p style=\"text-align: left\"><span style=\"color: #000000\"><span style=\"font-size: x-large\">In the Bridges lab, we study how bacteria make developmental decisions based on extracellular sensory information. We combine imaging approaches with techniques including genetics, biochemistry, and automation to discover and characterize the molecular mechanisms that bacteria use to control their behaviors. Our long term goal is to develop new<\/span><span style=\"font-size: x-large\"> ways to manipulate bacterial behavior, potentially leading to new strategies for controlling disease. We strive to create an engaging, diverse, inclusive, and immersive intellectual atmosphere for trainees. Join us on the adventure!<\/span><\/span><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_row_2 et_pb_row et_block_row\">\n<div class=\"et_pb_column_2 et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_video_0 et_pb_video et_pb_module et_block_module\"><div class=\"et_pb_video_box\"><iframe loading=\"lazy\" title=\"CMU Experts: What If Infections Could be Treated Without Antibiotics?\" width=\"1080\" height=\"608\" src=\"https:\/\/www.youtube.com\/embed\/mJ9wvl8a9ts?feature=oembed\"  allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_row_3 et_pb_row et_block_row\">\n<div class=\"et_pb_column_3 et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_heading_1 et_pb_heading et_pb_module et_block_module\"><div class=\"et_pb_heading_container\"><h1 class=\"et_pb_module_header\">Developmental dynamics of bacterial communities<\/h1><\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_row_4 et_pb_row et_block_row\">\n<div class=\"et_pb_column_4 et_pb_column et_pb_column_2_5 et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_image_0 et_pb_image et_pb_module et_block_module\"><span class=\"et_pb_image_wrap\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2022\/08\/Model.png\" width=\"1995\" height=\"916\" srcset=\"https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2022\/08\/Model.png 1995w, https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2022\/08\/Model-1280x588.png 1280w, https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2022\/08\/Model-980x450.png 980w, https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2022\/08\/Model-480x220.png 480w\" sizes=\"(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) and (max-width: 1280px) 1280px, (min-width: 1281px) 1995px, 100vw\" class=\"wp-image-142\" title=\"Model\" \/><\/span><\/div>\n<\/div>\n\n<div class=\"et_pb_column_5 et_pb_column et_pb_column_3_5 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_text_1 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p style=\"text-align: justify\">Bacteria are versatile organisms that modify their lifestyles in response to challenges encountered in their local environments. Commonly, bacteria overcome challenges by forming multicellular collectives known as biofilms, in which resident bacteria attach to surfaces and collectively produce an extracellular matrix. Advantages to constituent cells include protection from threats such as antimicrobial compounds, predation, and dislocation due to flow. The biofilm lifecycle consists of three developmental stages: founder cell attachment, biofilm maturation, and dispersal. In the Bridges lab, we use microscopy to define how bacteria transition between these stages.<\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_row_5 et_pb_row et_block_row\">\n<div class=\"et_pb_column_6 et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_heading_2 et_pb_heading et_pb_module et_block_module\"><div class=\"et_pb_heading_container\"><h1 class=\"et_pb_module_header\">Molecular mechanisms of bacterial signal transduction<\/h1><\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_row_6 et_pb_row et_block_row\">\n<div class=\"et_pb_column_7 et_pb_column et_pb_column_2_5 et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_image_1 et_pb_image et_pb_module et_block_module\"><span class=\"et_pb_image_wrap\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2023\/11\/g2030.png\" width=\"1098\" height=\"1189\" srcset=\"https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2023\/11\/g2030.png 1098w, https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2023\/11\/g2030-980x1061.png 980w, https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2023\/11\/g2030-480x520.png 480w\" sizes=\"(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1098px, 100vw\" class=\"wp-image-352\" title=\"g2030\" \/><\/span><\/div>\n<\/div>\n\n<div class=\"et_pb_column_8 et_pb_column et_pb_column_3_5 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_text_2 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p style=\"text-align: justify\"><span style=\"color: #000000\">Bacteria frequently exhibit remarkable social behaviors, reminiscent of higher organisms, by collaborating with neighboring cells to perform group tasks. One common mechanism that bacteria use to gauge the cell density and species composition of their environments is via the secretion and detection of cell-to-cell signals. In the Bridges lab, we identify and examine the molecular mechanisms underpinning these signaling mechanisms. We are particularly interested in how bacteria distinguish \"kin\" from \"non-kin,\" in the context of the biofilm lifecycle. Moreover, we are increasingly interested in how bacteria living in complex environmental conditions integrate multiple stimuli simultaneously to make informed lifestyle decisions.<\/span><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_row_7 et_pb_row et_block_row\">\n<div class=\"et_pb_column_9 et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_heading_3 et_pb_heading et_pb_module et_block_module\"><div class=\"et_pb_heading_container\"><h1 class=\"et_pb_module_header\">Development of new tools to study bacterial communities<\/h1><\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_row_8 et_pb_row et_block_row\">\n<div class=\"et_pb_column_10 et_pb_column et_pb_column_2_5 et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_image_2 et_pb_image et_pb_module et_block_module\"><span class=\"et_pb_image_wrap\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2023\/09\/Combined_compressed-2-1.gif\" width=\"1068\" height=\"712\" srcset=\"https:\/\/labs.bio.cmu.edu\/bridges\/wp-content\/uploads\/sites\/33\/2023\/09\/Combined_compressed-2-1.gif 1068w\" sizes=\"(min-width: 0px) and (max-width: 480px) 480px, (min-width: 481px) and (max-width: 980px) 980px, (min-width: 981px) 1068px, 100vw\" class=\"wp-image-279\" title=\"Combined_compressed-2 (1)\" \/><\/span><\/div>\n<\/div>\n\n<div class=\"et_pb_column_11 et_pb_column et_pb_column_3_5 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_text_3 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p style=\"text-align: justify\"><span style=\"color: #000000\">In the Bridges lab, we strive to use whatever technique is necessary to answer a biological question, be it through our own technical expertise, collaboration, or the development of new tools. We are particularly interested in developing new tools that enable high-throughput evaluation of bacterial phenotypes and gene expression. To do so, we increasingly utilize robotics and automation. In addition to small-scale automation used in our own lab, Carnegie Mellon University has recently constructed an a remote laboratory hosing over 200 automated instruments that we will utilize to establish new protocols. Read more about the cloud lab <a href=\"https:\/\/cloudlab.cmu.edu\/\">here<\/a>.<\/span><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n\n<div class=\"et_pb_row_9 et_pb_row et_block_row\">\n<div class=\"et_pb_column_12 et_pb_column et_pb_column_4_4 et-last-child et_block_column et_pb_css_mix_blend_mode_passthrough\">\n<div class=\"et_pb_heading_4 et_pb_heading et_pb_module et_block_module\"><div class=\"et_pb_heading_container\"><h1 class=\"et_pb_module_header\">Publications<\/h1><\/div><\/div>\n\n<div class=\"et_pb_text_4 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p style=\"text-align: center\">Link to Drew's <a href=\"https:\/\/scholar.google.com\/citations?hl=en&amp;user=sT56ZRsAAAAJ&amp;view_op=list_works&amp;sortby=pubdate&amp;inst=3203679203499159833\">Google Scholar Page<\/a><\/p>\n<\/div><\/div>\n\n<div class=\"et_pb_text_5 et_pb_text et_pb_bg_layout_light et_pb_module et_block_module\"><div class=\"et_pb_text_inner\"><p><span style=\"color: #0a0a0a\">Mellick, S.N.S., Derringer, J.J., Boyes, D., Croteau, G., Burke, M., Gifford, S., Stark, D.J., Mike, L.A., Turecki, S., Carja, O., Mikheyeva, I.V., <strong>Bridges, A.A.<\/strong> (2026) Genome-scale label-free imaging reveals cellular physiology encoded in bacterial collective architecture. <em>bioRxiv<\/em>. doi: <a href=\"https:\/\/www.biorxiv.org\/content\/10.64898\/2026.08.30.748126v1\">10.64898\/2026.08.30.748126<\/a><\/span><\/p>\n<p><span style=\"color: #0a0a0a\">Kasivisweswaran, S., Prentice, J.A., <strong>Bridges, A.A. (2026) <\/strong>A branching cell-fate decision in biofilm dispersal enables long-term surface persistence. <em>bioRxiv<\/em>. PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42079082\/\">42079082<\/a><\/span><\/p>\n<p><span style=\"color: #0a0a0a\">Nguyen, E., Agbavor, C., Steenhaut, A., Pratyush M. R., Hiller, N. L., Cahoon, L. A., Mikheyeva, I. V., Ng, W.L., <strong>Bridges, A. A.<\/strong> (2025) A small periplasmic protein governs broad physiological adaptations in Vibrio cholerae via regulation of the DbfRS two-component system. <em>Nature Communications<\/em>. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41413053\/\"><span style=\"color: #0a0101\">PMID: <span style=\"color: #00ccff\">41413053<\/span><\/span><\/a><\/span><\/p>\n<p><span style=\"color: #0a0a0a\">MR, P., Prentice, J.A., Eutsey, R.A., Mikheyeva, I., Hiller, N.L., <strong>Bridges, A.A.<\/strong> (2025) Label-free microscopy enables high-throughput identification of genes controlling biofilm development. <em>bioRxiv<\/em>. PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40950160\/\">40950160<\/a><strong><\/strong><\/span><\/p>\n<p><span style=\"color: #0a0a0a\"><strong>Bridges, A. A<\/strong>, Guthrie, L., Lehman, M., Kellogg, E., Miranda, S., Pountain, A., Shriver, A., Varble, A., Kaplan, H., Shank, E., Storz, G. (2025) An Exciting Future for Microbial Molecular Biology and Physiology. <em>mBio<\/em>. PMID: <span style=\"color: #0070f9\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40586574\/\" style=\"color: #0070f9\">40586574<\/a><\/span><\/span><\/p>\n<p><span style=\"color: #000000\">Prentice, J.A., Kasivisweswaran, S., van de Weerd, R., <strong>Bridges, A. A.<\/strong> (2024) Biofilm dispersal patterns revealed using far-red fluorogenic probes. <a href=\"https:\/\/journals.plos.org\/plosbiology\/article?id=10.1371\/journal.pbio.3002928\">PLOS Biology<\/a>.<\/span><\/p>\n<p><span style=\"color: #000000;font-size: 20px\">Lass, S. W., Camphire, S., Smith, B. E., Eutsey, R. A., Prentice, J. A., Yerneni, S. S., Arun, A., <\/span><strong style=\"color: #000000;font-size: 20px\">Bridges, A. A.<\/strong><span style=\"color: #000000;font-size: 20px\">, Rosch, J.W., Conway, J. F., Campbell, P., Hiller, N. L. (2024) Pneumococcal Extracellular Vesicles Mediate Horizontal Gene Transfer via the Transformation Machinery. <a href=\"https:\/\/journals.asm.org\/doi\/10.1128\/msphere.00727-24\">mSphere<\/a>.<\/span><\/p>\n<p><span style=\"color: #000000\">Prentice, J.A., van de Weerd, R., <strong>Bridges, A. A.<\/strong> (2024) Cell-lysis sensing drives biofilm formation in Vibrio cholerae. <a href=\"https:\/\/www.nature.com\/articles\/s41467-024-46399-1\">Nature\u00a0 Communications<\/a>.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A.<\/strong> (2023) mSphere of Influence: The complex world of bacterial biogeography. <a href=\"https:\/\/journals.asm.org\/doi\/10.1128\/msphere.00628-23\">mSphere<\/a>.<\/span><\/p>\n<p style=\"text-align: center\"><strong><\/strong><\/p>\n<p style=\"text-align: center\"><strong>Papers pre-dating launch of the Bridges Lab<\/strong><\/p>\n<p><span style=\"color: #000000\">Prentice, J.A., <strong>Bridges, A. A.<\/strong>, Bassler, B. L. (2022) Synergy between c-di-GMP and Quorum-Sensing Signaling in Vibrio cholerae Biofilm Morphogenesis. Journal of Bacteriology e00249-22.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A.<\/strong>, Prentice, J.A., Wingreen, N.S., Bassler, B. L. (2022) Signal Transduction Network Principles Underlying Bacterial Collective Behaviors. Annual Review of Microbiology 76.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A.<\/strong>*, Prentice, J.A.*, Fei, C., Wingreen, N.S., Bassler, B. L. (2022) Quantitative input-output dynamics of a c-di-GMP signal-transduction cascade in Vibrio cholerae. PLoS Biology 20 (3).<\/span><br \/><span style=\"color: #000000\">*These authors contributed equally.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A<\/strong>. and Bassler, B. L. (2021) Inverse regulation of Vibrio cholerae biofilm dispersal by polyamine signals. eLife 10, e65487.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A.<\/strong>, Fei, C., Bassler, B. L. (2020) Identification of signaling pathways, matrix-digestion enzymes, and motility components controlling Vibrio cholerae biofilm dispersal. Proceedings of the National Academy of Sciences of the United States of America 117 (51), 32639-32647.<\/span><\/p>\n<p><span style=\"color: #000000\">Qin, B., Fei, C., <strong>Bridges, A. A<\/strong>., Mashruwala, A., Stone, H., Wingreen, N. S., Bassler, B. L. (2020) Cell fates and collective fountain flow in bacterial biofilms revealed by light-sheet microscopy. Science 369, 71-77.<\/span><\/p>\n<p><span style=\"color: #000000\">Silpe, J. E.*, <strong>Bridges, A. A<\/strong>*., Huang X., Coronado D. R., Duddy O. P., Bassler B. L. (2020) Separating functions of the phage-encoded quorum-sensing-activated antirepressor Qtip. Cell Host &amp; Microbe 27, 629\u2013641.<\/span><br \/><span style=\"color: #000000\">*These authors contributed equally.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A.<\/strong> and Bassler, B. L. (2019) The intra-genus and inter-species quorum-sensing autoinducers exert distinct control over Vibrio cholerae biofilm formation and dispersal. PLoS Biology 17, 11.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A.<\/strong>, and Gladfelter, A. S. (2016) Septin complexes assemble during a kinetic window of opportunity. Cell cycle 11, 1-2.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A.<\/strong>, and Gladfelter, A. S. (2016) In vitro reconstitution of septin assemblies on supported lipid bilayers. Methods in Cell Biology 136, 57-71.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A.<\/strong>, Jentzsch, M. S., Occhipinti, P. Oakes, P.W., Gladfelter, A. S. (2016) Micron-scale plasma membrane curvature is recognized by the septin cytoskeleton. Journal of Cell Biology 213, 23-32.<\/span><\/p>\n<p><span style=\"color: #000000\">Zhang, H., Elbaum-Garfinkle, S., Langdon, E.M., Taylor, N., Occhipinti, P., <strong>Bridges, A. A.<\/strong>, Brangwynne, C. P., Gladfelter, A. S. (2015) RNA controls polyQ protein phase transitions. Molecular Cell 60, 220-230.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A.<\/strong>, and Gladfelter, A. S. (2015) Septin form and function at the cell cortex. The Journal of Biological Chemistry 290, 17173-17180.<\/span><\/p>\n<p><span style=\"color: #000000\">Kaplan, C., Jing, B., Winterflood, C. M., <strong>Bridges, A. A.<\/strong>, Occhipinti, P., Schmied, J., Grinhagens, S., Gronemeyer, T., Tinnefeld, P., Gladfelter, A. S., Ries, J., and Ewers, H. (2015) Absolute arrangement of subunits in cytoskeletal septin filaments in cells Measured by fluorescence microscopy. Nano Letters 15, 3859-3864.<\/span><\/p>\n<p><span style=\"color: #000000\">4. <strong>Bridges, A. A.<\/strong>, and Gladfelter, A. S. (2014) Fungal pathogens are platforms for discovering novel and conserved septin properties. Current Opinion in Microbiology 20, 42-48.<\/span><\/p>\n<p><span style=\"color: #000000\">Bahl, C. D., Hvorecny, K. L., <strong>Bridges, A. A.<\/strong>, Ballok, A. E., Bomberger, J. M., Cady, K. C., O'Toole, G. A., and Madden, D. R. (2014) Signature motifs identify an Acinetobacter Cif virulence factor with epoxide hydrolase activity. The Journal of Biological Chemistry 289, 7460-7469.<\/span><\/p>\n<p><span style=\"color: #000000\"><strong>Bridges, A. A.<\/strong>, Zhang, H., Mehta, S. B., Occhipinti, P., Tani, T., and Gladfelter, A. S. (2014) Septin assemblies form by diffusion-driven annealing on membranes. Proceedings of the National Academy of Sciences of the United States of America 111, 2146-2151.<\/span><\/p>\n<p><span style=\"color: #000000\">Sellin Jeffries, M. K., Conoan, N. H., Cox, M. B., Sangster, J. L., Balsiger, H. A., <strong>Bridges, A. A.<\/strong>, Cowman, T., Knight, L. A., Bartelt-Hunt, S. L., and Kolok, A. S. (2011) The anti-estrogenic activity of sediments from agriculturally intense watersheds: assessment using in vivo and in vitro assays. Aquatic Toxicology 105, 189-198.<\/span><\/p>\n<\/div><\/div>\n<\/div>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":10,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-22","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labs.bio.cmu.edu\/bridges\/wp-json\/wp\/v2\/pages\/22","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.bio.cmu.edu\/bridges\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.bio.cmu.edu\/bridges\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.bio.cmu.edu\/bridges\/wp-json\/wp\/v2\/users\/10"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.bio.cmu.edu\/bridges\/wp-json\/wp\/v2\/comments?post=22"}],"version-history":[{"count":58,"href":"https:\/\/labs.bio.cmu.edu\/bridges\/wp-json\/wp\/v2\/pages\/22\/revisions"}],"predecessor-version":[{"id":680,"href":"https:\/\/labs.bio.cmu.edu\/bridges\/wp-json\/wp\/v2\/pages\/22\/revisions\/680"}],"wp:attachment":[{"href":"https:\/\/labs.bio.cmu.edu\/bridges\/wp-json\/wp\/v2\/media?parent=22"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}