{"id":11,"date":"2021-10-15T17:01:27","date_gmt":"2021-10-15T17:01:27","guid":{"rendered":"https:\/\/labs.bio.cmu.edu\/cai\/?page_id=11"},"modified":"2024-03-15T17:02:05","modified_gmt":"2024-03-15T17:02:05","slug":"home","status":"publish","type":"page","link":"https:\/\/labs.bio.cmu.edu\/cai\/","title":{"rendered":"Welcome to the Cai Lab!"},"content":{"rendered":"<p style=\"text-align: center\">T cells are essential defenders in the body\u2019s battle against harmful invaders. They are constantly on the lookout for unfamiliar substances displayed on the surfaces of host cells. As a critical part of anti-tumor immunity, T cells detect cancer cells and trigger immune responses to eliminate them. However, T cell functions are often impaired in the tumor microenvironment, making them ineffective at killing cancer cells. Our lab focuses our research on understanding the fundamental mechanisms of T cell anti-tumor immunity in the tumor microenvironment using high-resolution imaging approaches. Our long-term goal is to uncover insights that may advance current cancer immunotherapy strategies.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-356 \" src=\"https:\/\/labs.bio.cmu.edu\/cai\/wp-content\/uploads\/sites\/30\/2024\/03\/unnamed-e1710522098590.png\" alt=\"\" width=\"710\" height=\"367\" srcset=\"https:\/\/labs.bio.cmu.edu\/cai\/wp-content\/uploads\/sites\/30\/2024\/03\/unnamed-e1710522098590.png 2455w, https:\/\/labs.bio.cmu.edu\/cai\/wp-content\/uploads\/sites\/30\/2024\/03\/unnamed-e1710522098590-300x155.png 300w, https:\/\/labs.bio.cmu.edu\/cai\/wp-content\/uploads\/sites\/30\/2024\/03\/unnamed-e1710522098590-1024x529.png 1024w, https:\/\/labs.bio.cmu.edu\/cai\/wp-content\/uploads\/sites\/30\/2024\/03\/unnamed-e1710522098590-768x397.png 768w, https:\/\/labs.bio.cmu.edu\/cai\/wp-content\/uploads\/sites\/30\/2024\/03\/unnamed-e1710522098590-1536x794.png 1536w, https:\/\/labs.bio.cmu.edu\/cai\/wp-content\/uploads\/sites\/30\/2024\/03\/unnamed-e1710522098590-2048x1059.png 2048w\" sizes=\"auto, (max-width: 710px) 100vw, 710px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>T cells are essential defenders in the body\u2019s battle against harmful invaders. They are constantly on the lookout for unfamiliar substances displayed on the surfaces of host cells. As a critical part of anti-tumor immunity, T cells detect cancer cells and trigger immune responses to eliminate them. However, T cell functions are often impaired in [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"class_list":["post-11","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/labs.bio.cmu.edu\/cai\/wp-json\/wp\/v2\/pages\/11","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/labs.bio.cmu.edu\/cai\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/labs.bio.cmu.edu\/cai\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/labs.bio.cmu.edu\/cai\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/labs.bio.cmu.edu\/cai\/wp-json\/wp\/v2\/comments?post=11"}],"version-history":[{"count":15,"href":"https:\/\/labs.bio.cmu.edu\/cai\/wp-json\/wp\/v2\/pages\/11\/revisions"}],"predecessor-version":[{"id":358,"href":"https:\/\/labs.bio.cmu.edu\/cai\/wp-json\/wp\/v2\/pages\/11\/revisions\/358"}],"wp:attachment":[{"href":"https:\/\/labs.bio.cmu.edu\/cai\/wp-json\/wp\/v2\/media?parent=11"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}