Welcome to the Barth Lab!

Research in the Barth lab is focused on understanding how experience assembles and alters the properties of neural circuits in the cerebral cortex, in both normal and disease states.

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  The cover art for Journal of Neuroscience January 2023! POm thalamacortical inputs show specfic plasticity on to compartments of L5 Pyramidal neurons
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  POm thalamocortical input drives layer-specific microcircuits in somatosensory cortex.
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  Unbiased, high-throughput electron microscopy analysis of experience-dependent synaptic changes in the neocortex.
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  Gephyrin-FingR labeling of PV synapses onto cortical pyramidal neurons
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  Experience dependent plasticity in somatosensory cortex.
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  Network assembly and optimization using principles of neural design.
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  alt textExperience dependent plasticity in somatosensory cortex.
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  GFP labelled population of somatostatin containing neocortical interneurons.
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  GABAb receptors silence excitatory synapses in the neocortex.
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  Single-whisker experience enhances response to low-intensity stimuli. © Elena Peterson
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  Quantitative synapse analysis for cell-type specific connectomics.
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  Precisely Timed Nicotinic Activation Drives SST Inhibition in Neocortical Circuits.

Recent Lab News

May 2024 – Joanne Steinmiller retires after 14 years as lab manager in the Barth Lab

May 2024 – Alison elected as a AAAS fellow

April 2024 – Mo Zhu’s paper accepted as the cover article at Learning and Memory

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