Publications

Molinar-Inglis O, Oliver SL, Davison P, Kunttas E, McCartney BM. APC2 associates with the actin cortex through a multi-part mechanism to regulate  cortical actin organization and dynamics in the Drosophila ovary. Cytoskeleton (Hoboken). 2018 Jul; doi: 10.1002/cm.21471.

Blundon MA, Schlesinger DR, Parthasarathy A, Smith SL, Kolev HM, Vinson DA, Kunttas-Tatli E, McCartney BM, Minden JS. Proteomic analysis reveals APC-dependent post-translational modifications and identifies a novel regulator of β-catenin. Development. 2016 Jul 15;143(14):2629-40.

Fouz MF, Mukumoto K, Averick S, Molinar O, McCartney BM, Matyjaszewski K, Armitage BA, Das SR. right Fluorescent Nanotags from Bottlebrush Polymers with DNA-Tipped Bristles. ACS Cent Sci. 2015 Nov 25;1(8):431-8.

Kunttas-Tatli E, Von Kleeck RA, Greaves BD, Vinson D, Roberts DM, McCartney BM. The two SAMP repeats and their phosphorylation state in Drosophila Adenomatous polyposis coli-2 play mechanistically distinct roles in negatively regulating Wnt signaling. Mol Biol Cell. 2015 Dec 1;26(24):4503-18.

Kunttas-Tatli E, Roberts DM, McCartney BM. Self-association of the APC tumor suppressor is required for the assembly, stability, and activity of the Wnt signaling destruction complex. Mol Biol Cell. 2014 Sep 10.

Komori H, Xiao Q, McCartney BM, Lee CY. Brain tumor specifies intermediate progenitor cell identity by attenuating β-catenin/Armadillo activity. Development. 2014 Jan;141(1):51-62

Jaiswal R, Stepanik V, Rankova A, Molinar O, Goode BL, McCartney BM. Drosophila homologues of adenomatous polyposis coli (APC) and the formin diaphanous collaborate by a conserved mechanism to stimulate actin filament assembly. J Biol Chem. 2013 May 10;288(19):13897-905.

Kunttas-Tatli E, Zhou MN, Zimmerman S, Molinar O, Zhouzheng F, Carter K, Kapur M, Cheatle A†, Decal R, McCartney BM*. Destruction complex function in the Wnt signaling pathway of Drosophila requires multiple interactions between Adenomatous polyposis coli 2 and Armadillo. Genetics. 2012 Mar;190(3):1059-75. Epub 2011 Dec 14.

Stadler AL, Delos Santos JO, Stensrud ES, Dembska A, Silva GL, Liu S, Shank NI, Kunttas-Tatli E, Sobers CJ, Gramlich PM, Carell T, Peteanu LA, McCartney BM, Armitage BA. Fluorescent DNA Nanotags Featuring Covalently Attached Intercalating Dyes: Synthesis, Antibody Conjugation and Intracellular Imaging. Bioconjugate Chemistry 22(8):1491-1502, 2011 Aug 17.

Zhou M-N, Kunttas-Tatli E, Zimmerman S, Zhouzheng F, McCartney BM. Cortical localization of APC2 plays a role in actin organization but not in Wnt signaling in Drosophila. Journal of Cell Science, 124(Pt 9):1589-600, 2011 May 1.

Zimmerman SG, Thorpe LM, Medrano VR, Mallozzi CA, McCartney BM. Apical constriction and invagination downstream of the canonical Wnt signaling pathway requires Rho1 and Myosin II. Developmental Biology 340:54-66, 2010.

Webb RL, Rozov O, Watkins S, McCartney BM. Using Total Internal Reflection Fluorescence (TIRF) microscopy to visualize cortical actin and microtubules in the Drosophila syncytial embryo. Developmental Dynamics; 238:2622-2632, 2009.

Webb RL, Zhou MN, McCartney BM. A novel role for an APC2-Diaphanous complex in regulating actin organization in Drosophila. Development; 136(8):1283-93, 2009 Apr. Epub 2009 Mar 11.

McCartney BM, Näthke IS. Cell regulation by the Apc protein Apc as master regulator of epithelia. Curr Opin Cell Biol 2008 Apr; 20(2):186-93, Epub 2008 Mar 24.

McCartney BM, Price MH, Webb RL, Hayden MA, Holot LM, Zhou M, Bejsovec A, Peifer M. Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila. Development; 133(12):2407-18, 2006 Jun.

Akong K, McCartney BM and Peifer M. Drosophila APC2 and APC1 have overlapping roles in the larval brain despite their distinct intracellular localizations. Developmental Biology, 250(1):71-90, 2002.

Akong K, Grevengoed E, Price M, McCartney BM, Hayden M, DeNofrio J and Peifer M. Drosophila APC2 and APC1 play overlapping roles in Wingless signaling in the embryo and imaginal discs. Developmental Biology, 250(1):91-100, 2002.

McCartney B, McEwen, Grevengoed E, Maddox P, Bejsovec A and Peifer M. Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin. Nature Cell Biology, 3(10):933-938, 2001.

McCartney BM and Peifer M. Teaching tumour suppressors new tricks. Nature Cell Biology, 2(4): E58-E60, 2000.

McCartney BM, Dierick HA, Kirkpatrick C, Moline M, Baas A, Peifer M and Bejsovec A. Drosophila APC2 is a cytoskeletally-associated protein that regulates Wingless signaling in the embryonic epidermis. Journal of Cell Biology, 146(6):1303-1318, 1999.