Rm 634 Mellon Institute
4400 5th Ave
Office Phone: email me
Phone Lab: 412 268 9290
I manage the Echinobase website, now hosted at CMU, and am actively working to improve genome assemblies and annotations for a variety of Echinoderm species to empower comparative genomics approaches. I am also interested in understanding how low-affinity binding sites evolve and the consequences of low-affinity binding on the evolution of GRNs.
Evolution of GRNs across embryo, larval and adult life phases. I’m studying how GRNs can co-opt to produce novel phenotypes and for convergence of phenotypes. I’m also interested in understanding the function of highly conserved noncoding elements.
Biological systems are diverse and complex and span many levels of organization and time. Evolution performs experiments very slowly, genomics analyzes changes and genetic engineering allows for the rapid testing of gene expression and modifications. During many years of research I have been very fortunate to work with a wide variety of scientists using many different experimental approaches. In the Hinman Lab I look forward to being involved with Echinobase and exciting genomics research, and contributing to developmental and regeneration studies using these fascinating marine organisms.
I am working to develop pipelines for streamlining the annotation of orthologs between echinoderms and other species.
I am working to understand the Cellular control of regeneration. I am identifying the populations of cells that initiate proliferation to reform lost tissue and want to understand how they are regulated to initiate proliferation.
I’m the main programmer for Echinobase and am responsible for coordinating with the database team in Calgary. I interact with members of the Echinobase scientific community to assist them, answer their bioinformatics-related questions and support data analysis and visual displays onto Echinobase. I also perform computational genomics work including genome assemblies, gene annotations, orthology predictions and determining non coding genomic information.
A very good boy. Will eat your socks if you don’t watch them carefully. 13/10
- Katherine Buckley. 2019. Assistant Professor, Auburn University
- Minyan (Mia) Zhang. 2019. (Postdoc, David Sinclair Lab, Harvard Medical School)
- Rene Francolini. Masters in Computational Biology. 2016. (Research Assistant, Jed Goldstone Lab, Woods Hole Oceanographic Institute)
- Alys Cheatle Jarvela. Ph.D. 2015. (Postdoc Leslie Pick. U. Maryland)
- Pradipata Ray. (Co-advised Eric Xing LTI). Ph.D. 2013. (Research Scientist, UT Dallas Center for Systems Biology)
- Brenna McCauley Ph.D. 2012. (Postdoc Baylor College Medicine).
- Sabah Kadri. Ph.D. 2012. (Associate Computational Biologist at Broad Institute, MIT)
- Kristen Yankura. Ph.D. 2012. (Postdoc UCLA)
- Stephanie Hughes. Masters Biological Sciences 2012
- Walter Lewis. Masters Computational Biology 2012
- Siyao Wang (2019). Honors Research. (Ph.D. Candidate, Duke University)
- Njairé Mckoy (2017)
- Katherine Huang (2017). Honors Research. (Ph.D. Candidate, UPenn)
- Nikkita Mishra
- Annette Ko (2015). HHMI researcher. NIH PostBac program
- Lazar Lalone (2014). Med School. UQ
- Sowyma Yennan (2014)
- Laura Filliger (2013). Honors Research. (PhD Candidate U. Rhode Island)
- Abigail Cryan (2013)
- Lisa Brubaker (2012). Honors Research. (NIH Postbaccalaureate)
- Megan Libonati (2012). (NIH Postbaccalaureate)
- Eda Akyar (2011). Honors Research. Fulbright Scholar 2011-2012. Yale MPH
- Claire Koechlein (2011) (PhD Candidate UCSD). Honors Research. Recipient Elizabeth Jones Award for Excellence in Undergraduate Research
- Ron Baski (2011)
- Cameron Exner (2010) (PhD Candidate UC Berkeley)
- Susan Alfs (2010) (Keck Graduate School)
- Charlotte Jennings (2009). Honors Research. (PhD Candidate UC Berkeley)
- Megan Martik (2009) (PhD Candidate Duke)
- Erin Weideman/Wright (2009) (Animal wildlife management program. London U.K.).
- Nicole Traphaggen (Clarkson College)
- Hala Rosa Saad (2011) (Brooklyn College). Now Ph.D. Columbia
- Jeremy Gale (2010) (Stockton College). Now PhD
- Karen Kormuth (2009) (Washington and Jefferson U.) Now CMU Ph.D. candidate in Biology.
- Amy Kerin (2008) (Washington and Jefferson U.).