Our lab uses proteomics, fluorescent probe development and time-lapse microscopy to study two central questions in developmental biology:
- Tissue morphogenesis: Embryo development is typified by a tremendous amount of cell movement. How do the cells in fruit fly (Drosphilia) embryos change their shape to drive tissue morphogenesis?
- Programmed cell death: Programmed cell death (apoptosis) plays a central role in embryonic development. How do cells decide to die to maintain tissue homeostasis? (more)