Zhang Lab @ CMU

We are a team of scientists and engineers integrating tools from multiple disciplines to investigate how cells work. Our current focus is to study how phase transition organizes biochemistry in healthy and cancer cells by combing optogenetic manipulation, live cell imaging, in vitro reconstitution, biophysical quantification and  mathematic modeling. The end goal is to engineer synthetic organelles and develop cancer therapies.

Welcome to Huaiying Zhang’s lab at Carnegie Mellon University!

If you are passionate about using multidisciplinary techniques to reveal fundamental principles in cell biology and provide insights for cancer therapy, join us!

We are recruiting lab members at all levels.
Liquid condensation on telomeres drives telomere clustering in telomerase-free cancer cells.

The website is currently undergoing construction for a redesign. 

Check back with us soon!

Highlights

  • Optogenetic control of kinetochore function. Nature Chemical Biology, 2017

 

  • RNA controls polyQprotein phase transitions. Molecular Cell, 2015.