Publications

TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells

M. Xu, D. Senanayaka, R. Zhao, T. Chigumira, A. Tripathi, J. Tones, R. M. Lackner, A. R. Wondisford, L. N. Moneysmith, A. Hirschi, S. Craig, S. Alishiri, R. J. O’Sullivan, D. M. Chenoweth, N. J. Reiter & H. Zhang

Nature Communications, 2024

Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project

J. Dekker, F. Alber, S. Aufmkolk, B. J. Beliveau, B. G. Bruneau, A. S. Belmont, L. Bintu, A. Boettiger, R. Calandrelli, C. M. Disteche, D. M. Gilbert, T. Gregor, A. S. Hansen, B. Huang, D. Huangfu, R. Kalhor, C. S. Leslie, W. Li, Y. Li, J. Ma, W. S. Noble, P. J. Park, J. E. Phillips-Cremins, K. S. Pollard, S. M. Rafelski, B. Ren, Y. Ruan, Y. Shav-Tal, Y. Shen, J. Shendure, X. Shu, C. Strambio-De-Castillia, A. Vertii, H. Zhang, S. Zhong

Molecular Cell, 2023

Frontiers in biomolecular condensate research

C. Mayr, T. Mittag, T.-Y. D. Tang, W. Wen, H0. Zhang, H. Zhang

Nature Cell Biology, 2023

S. Boeynaems, S. Chong, J. Gsponer, L. Holt, D. Milovanovic, D. M. Mitrea, O. Mueller-Cajar, B. Portz, J. F. Reilly, C. D. Reinkemeier, B. R. Sabari, S. Sanulli, J. Shorter, E. Sontag, L. Strader, J. Stachowiak, S. C. Weber, M. White, H. Zhang, M. Zweckstetter, S. Elbaum-Garfinkle, R. Kriwacki

Journal of Molecular Biology , 2023

RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA

N. Kaminski, A. R. Wondisford, Y. Kwon, M. L Lynskey, R. Bhargava, J. Barroso-González, L. García-Expósito, B. He, M. Xu, D. Mellacheruvu, S. C. Watkins, M. Modesti, K. M. Miller, A. I. Nesvizhskii, H. Zhang, P. Sung, R. J. O’Sullivan

Molecular Cell, 2022

CRISPR Cas13-Based Tools to Track and Manipulate Endogenous Telomeric Repeat-Containing RNAs in Live Cells

M. Xu , T. Chigumira, Z. Chen, J. Tones, R. Zhao, K. N. Dahl, D. M. Chenoweth, H. Zhang

Frontiers in Molecular Biosciences, 2022

Chemical dimerization-induced protein condensates on telomeres (PDF)

R. Zhao, D. M. Chenoweth, H. Zhang

Journal of Visualized Experiments, 2021, e62173

Tension promotes kinetochore-microtubule release by Aurora B kinase (PDF)

G-Y Chen, F Renda, H. Zhang, A. Gokden, D. Z. Wu, D. M. Chenoweth, A. Khodjakov, M. A. Lampson

Journal of Cell Biology , 2021

The glassiness of hardening protein droplets (PDF)

Huaying Zhang

Science, 2020

Nuclear body phase separation drives telomere clustering in ALT cancer cells (PDF)

Huaiying Zhang, Rongwei Zhao, Jason Tones, Michel Liu, Robert Dilley, David M. Chenoweth, Roger A. Greenberg, and Michael A. Lampson

Molecular Biology of the Cell, 2020

Reversible control of protein localization in living cells using a photocaged-photocleavable chemical dimerizer (PDF)

C. Aonbangkhen,H. Zhang, D. Wu, M. A. Lampson, D.M. Chenoweth

Journal of the American Chemical Society, 2018

Optogenetic control of mitosis with photocagedchemical dimerizers (PDF)

H. Zhang, D. M. Chenoweth, and M. A. Lampson.

Methods in Cell Biology – Mitosis & Meiosis, 2018.

Optogenetic control of kinetochore function (PDF)

H. Zhang*, C. Aonbangkhen*, E Tarasovetc, E. R. Ballister, D. M. Chenoweth, M. A. Lampson (*equal contribution)

Nature Chemical Biology, 2017.

Also see highlights:
Kinetochore regulation: Let there be light by Ana C Figueiredo & Helder Maiato in Nature Chemical Biology.

Cell biology: Optimized light-dependent dimerization in Nature Methods.
Recommended in F1000Prime as being of special significance by Paramjit Arora.

Biophysical characterization of organelle-based RNA/protein liquid phases using microfluidics (PDF)

N. Taylor, S. Elbaum-Garfinkle, N. Vaidya, H. Zhang, H. A. Stone, C. P. Brangwynne

Soft Matter, 2016

RNA controls polyQ protein phase transitions (PDF)

H. Zhang, S. Elbaum-Garfinkle, E. M. Langdon, N. Taylor, P. Occhipinti, A. A. Bridges, C. P. Brangwynne, and A. S. Gladfelter.

Molecular Cell, 2015

Highlighted in:

It’s Raining Liquids: RNA Tunes Viscoelasticity and Dynamics of Membraneless Organelles by L. Guo and J. Shorter.

Featured in Meet The Author.

Coupling between cytoplasmic concentration gradients through local control of protein mobility in the Caenorhabditis elegans zygote (PDF)

Y. Wu, H. Zhang, E. E. Grifin

Molecular Biology of the Cell, 2015

Ploidy variation in multinucleate cells changes under stress (PDF)

C. A. Anderson, S. Roberts*, H. Zhang*, C. M. Kelly, A. Kendall, C. Lee, J. Gerstenberger, A. B. Koenig, R. Kabeche, and A. S. Gladfelter (*equal contribution)

Molecular Biology of the Cell, 2015

Septin assemblies form by diffusion-driven annealing on membranes (PDF)

A. A. Bridges, H. Zhang, S. Mehta, P. Occhipinti, T. Tani, A. S. Gladfelter

Proceedings of the National Academy of Sciences, 2014

Protein aggregation behavior regulates cyclin transcript localization and cell-cycle control (PDF)

C. Lee, H. Zhang, A. E. Baker, P. Occipinti, M. E. Borsuk, A. S. Gladfelter

Developmental Cell, 2013

Lipopolymer gradient diffusion in supported bilayer membranes (PDF)

H. Zhang, R. J. Hill

Journal of Royal Society Interface, 2011

Concentration dependence of lipopolymer self-diffusion in supported bilayer membranes (PDF)

H. Zhang, R. J. Hill

Journal of Royal Society Interface, 2011

Lipopolymer electrophoresis in supported bilayer membranes (PDF)

H. Zhang, R. J. Hill

Soft Matter, 2010

Selection of adsorbents in the coupling technology of adsorption desulfurization and biodesulfurization (PDF)

H. Zhang, Q. Liu, Y. Li, W. LI, X. Xiong, J. Xing, H. Liu

Science in China Series B: Chemistry, 2007

Preparation of (Ni/W)-γ-Al2O3 microspheres and its application in adsorption desulfurization for model gasoline (PDF)

H. Zhang, G. Shan, J. Xing, H. Liu

Chemical Engineering Communications, 2007

Improvement of biodesulfurization rate by assembling nanosorbents on the surfaces of microbial cells (PDF)

G. Shan, H. Zhang, W. Cai, J. Xing, H. Liu

Biophysical Journal, 2005

4. Biodesulfurization of hydrodesulfurized diesel oil with Pseudomonas delaﬁeldii R-8 from high density culture (PDF)

G. Shan, H. Zhang, J. Xing, G. Chen, W. Li, H. Liu

Biochemical Engineering Journal, 2006, 27: 305-309

Biodesulfurization of dibenzothiophene by microbial cells coated with magnetite nanoparticles (PDF)

G. Shan, J. Xing, H. Zhang, H. Liu

Applied Environmental Microbiology, 2005

π-complexation studied by ﬂuorescence technique: Application in desulfurization of petroleum product using magnetic π-complexation sorbents

G. Shan, H. Zhang, H. Liu, J. Xing

Separation Science and Technology, 2005

Deep desulfurization of hydrodesulfurized diesel oil by Pseudomonas delaﬁeldii R-8 (PDF)

G. Shan, J. Xing, H. Zhang, H. Liu

Journal of Chemical Technology and Biotechnology, 2005

Publications

TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells

Spatial and temporal organization of the genome: Current state and future aims of the 4D nucleome project

Frontiers in biomolecular condensate research

Phase Separation in Biology and Disease; Current Perspectives and Open Questions

RAD51AP1 regulates ALT-HDR through chromatin-directed homeostasis of TERRA

CRISPR Cas13-Based Tools to Track and Manipulate Endogenous Telomeric Repeat-Containing RNAs in Live Cells

Chemical dimerization-induced protein condensates on telomeres (PDF)

Tension promotes kinetochore-microtubule release by Aurora B kinase (PDF)

The glassiness of hardening protein droplets (PDF)

Nuclear body phase separation drives telomere clustering in ALT cancer cells (PDF)

Reversible control of protein localization in living cells using a photocaged-photocleavable chemical dimerizer (PDF)

Optogenetic control of mitosis with photocagedchemical dimerizers (PDF)

Optogenetic control of kinetochore function (PDF)

Biophysical characterization of organelle-based RNA/protein liquid phases using microfluidics (PDF)

RNA controls polyQ protein phase transitions (PDF)

Coupling between cytoplasmic concentration gradients through local control of protein mobility in the Caenorhabditis elegans zygote (PDF)

Ploidy variation in multinucleate cells changes under stress (PDF)

Septin assemblies form by diffusion-driven annealing on membranes (PDF)

Protein aggregation behavior regulates cyclin transcript localization and cell-cycle control (PDF)

Lipopolymer gradient diffusion in supported bilayer membranes (PDF)

Concentration dependence of lipopolymer self-diffusion in supported bilayer membranes (PDF)

Lipopolymer electrophoresis in supported bilayer membranes (PDF)

Selection of adsorbents in the coupling technology of adsorption desulfurization and biodesulfurization (PDF)

Preparation of (Ni/W)-γ-Al2O3 microspheres and its application in adsorption desulfurization for model gasoline (PDF)

Improvement of biodesulfuriza­tion rate by assembling nanosorbents on the surfaces of microbial cells (PDF)

4. Biodesulfurization of hydrodesulfurized diesel oil with Pseudomonas delaﬁeldii R-8 from high density culture (PDF)

Biodesulfurization of dibenzothiophene by microbial cells coated with magnetite nanoparticles (PDF)

π-complexation studied by ﬂuorescence technique: Application in desulfurization of petroleum product using magnetic π-complexation sorbents

Deep desulfurization of hydrodesulfurized diesel oil by Pseudomonas delaﬁeldii R-8 (PDF)

Improvement of biodesulfurization rate by assembling nanosorbents on the surfaces of microbial cells (PDF)