The Zhang Lab

Principal Investigator

image of Zhang Huaiying

Huaiying Zhang

Assistant Professor

Department of Biological Sciences, Carnegie Mellon University

Department of Chemical Engineering (courtesy), Carnegie Mellon University

Molecular Biophysics and Structural Biology (MBSB) graduate program, Carnegie Mellon University & University of Pittsburgh

Department of Physics, Carnegie Mellon University

Contact: huaiyinz@andrew.cmu.edu

Education and Training

Postdoctoral fellow

Ph.D., Chemical Engineering, McGill University, lab of Dr. Reghan Hill
M.S., Chemical Technology, Chinese Academy of Sciences, lab of Dr. Jianming Xing and Dr. Huizhou Liu
B.E., Applied Chemistry, China University of Mining and Technology (Beijing)

Postdoctoral Fellows

Xiaoyang Yu

Ph.D. in Microbiology and Immunology at University of Pittsburgh, School of Medicine

Contact: xyu4@andrew.cmu.edu

I’m from Beijing, China, and I conducted my PhD research on the HBV at University of Pittsburgh.
Immediately after completing my PhD in 2023, I joined the Zhang lab. In my leisure time, I enjoy painting and cuddling with my dog.

 

Biplab KC

Ph.D. in Systems Life Sciences at Kyushu University, Japan

Contact: biplabk@andrew.cmu.edu

I completed my Ph.D. at Katayama Lab, from Kyushu University, Japan under the supervision of Prof. Akihiro Kishimura. During my Ph.D., I worked on liquid-liquid phase separation in poly-ionic material and got fascinated with the self-assembly process for condensate formation. Now, I want to work on intracellular condensate which led me to the Zhang lab where I am studying photo-sensitive chemical-induced dimerization systems for modulating condensate inside the cells. My research will focus on understanding the SUMOylation process on condensate-forming proteins in understanding the ALT phenotype in cancer cells. During my free time, I like watching anime, playing badminton and table tennis, and hanging out with my friends.

Staff

image of Jason Tones with glasses

Jason Tones

Lab Manager

Contact: jasonton@andrew.cmu.edu

After 20 years in the restaurant industry and 3 years as a stay home dad I earned my microbiology degree in 2018 and began working in the Zhang lab in 2019. In my free time I like to make pasta, try my hand at home fermentation, and occasionally golf.

 

image of female with glasses surrounded by balloons

Sophia DeGuara

Research Associate

Contact:sdeguara@andrew.cmu.edu

In May of 2024, I received my bachelors degree in Biology with a minor in Psychological Sciences from Penn State University where I was also a student athlete. I’ve always had a passion for research, which grew as I completed two years of undergraduate work in a Biochemistry & Molecular Biology Lab studying Alzheimer’s Disease. As a postbac in the Zhang lab at CMU, I hope to continue using my curiosity and creativeness to produce meaningful research. Outside of lab I enjoy baton twirling, yoga, and music!

 

 

Graduate Students

Tafadzwa Chigumura

Ph.D. Candidate in Chemical Engineering

Contact: tchigumi@andrew.cmu.edu

I completed my master’s in Chemical Engineering at Howard University and moved right into the PhD program at CMU. I’m looking forward to delving into the world of cell biology and discovering extended applications of chemical engineering principles. My hobbies include listening to audible books, watching C, K and Thai dramas and hunting down good (and cheap) food.

image of Rongwei Zhao

Rongwei Zhao

Ph.D. Candidate in Biological Sciences

Contact: rongweiz@andrew.cmu.edu

I am from Beijing, China. Among the various fields in biology, molecular and cell biology intrigues me most because it not only allows us to elucidate the unknown mechanism of cell regulation, but is also essential for discovery and development of therapeutics and pharmaceuticals in the long run. In my free time I like hiking, traveling and appreciating sweeties.

 

image of a young man

Jasper Jeffrey

Ph.D. candidate in Molecular Biophysics and Structural Biology (MBSB)

Contact: jdjeffre@andrew.cmu.edu

After receiving my B.Sc. from Lehigh University, I worked on performing single molecule experiments with the Kinesin 1 motor KIF1A and general anesthetic propofol. At the Zhang lab I am currently elucidating structural features that drive liquid-liquid phase separation of proteins involved in cell division. When outside the lab space I enjoy scale modeling, visiting submarines and being an amateur green thumb.

 

image of Ruwani Dalath

Ruwani Madushika Dalath

Ph.D. Candidate in Biological Sciences

Contact: rdalath@andrew.cmu.edu

Ever since I got to know that the biochemical and molecular changes at the cellular level lead to physiological alterations in living creatures , my desire to dive more into this regard grew up day by day! With my eyes focused on my passion, I pursued my bachelor’s degree in Molecular Biology and Biochemistry at the University of Colombo and moved right into my PhD in Biological Sciences at CMU! I joined Zhang lab in May 2023 and here I am exploring more in the world of science and doing What I’ve always wanted to do!!!

 

image of Ruwani Dalath

William Wu

M.S student in Biotechnology and Pharmaceutical Engineering

Contact: weifeng2@andrew.cmu.edu

I am currently a Master’s student in Biotechnology and Pharmaceutical Engineering at
Carnegie Mellon University. I had my training in molecular and cell biology from my undergraduate studies at New York University. Prior to joining CMU, I worked as a healthcare analyst in the Investment Banking industry.

 

Undergraduate Students

Allison Wivagg

Major in Biological Sciences

Contact: awivagg@andrew.cmu.edu

 

image of man with backpack climbing mountains

Chris Bi

Major in Biological Sciences

Contact: ziangb@andrew.cmu.edu

I am an undergraduate student currently majoring in Biological Sciences. I joined Zhang lab in 2023 and am thrilled to contribute to researches in protein condensates. In my free time I enjoy practicing with my bandmates and going to concerts.

 

Stephen Wu

Major in Biological Sciences

Contact: shuangw2@andrew.cmu.edu

 

Lab Alumni

Anh Thu Pham, Master’s Student- Currently at University of Pittsburgh

Meng Xu, Postdoctoral Fellow- Currently at NIH

Lu Qiao, Master’s Student- Currently at Yale University

Will O’Connell, Master’s Student – Currently at FlexTrade Systems Inc.

Sabrina Tsai, Master’s Student – Currently at Altius Institute for Biomedical Sciences.

Astha Tripathi, Undergraduate Researcher – Currently at Massachussetts General Hospital.